DISPIROKETALS IN SYNTHESIS .16. FUNCTIONALIZED DISPIROKETALS AS NEW CHIRAL AUXILIARIES - THE SYNTHESIS OF DIHYDROXYLATED DISPIROKETALS IN OPTICALLY PURE FORM AND THEIR APPLICATION AS BIFUNCTIONAL, C-2-SYMMETRICAL, CHIRAL AUXILIARIES FOR HIGHLY STEREOSELECTIVE MICHAEL ADDITIONS

Authors
BEZUIDENHOUDT BCB CASTLE GH INNES JE LEY SV
Citation
Bcb. Bezuidenhoudt et al., DISPIROKETALS IN SYNTHESIS .16. FUNCTIONALIZED DISPIROKETALS AS NEW CHIRAL AUXILIARIES - THE SYNTHESIS OF DIHYDROXYLATED DISPIROKETALS IN OPTICALLY PURE FORM AND THEIR APPLICATION AS BIFUNCTIONAL, C-2-SYMMETRICAL, CHIRAL AUXILIARIES FOR HIGHLY STEREOSELECTIVE MICHAEL ADDITIONS, Recueil des travaux chimiques des Pays-Bas, 114(4-5), 1995, pp. 184-194
Citations number
45
Categorie Soggetti
Chemistry
Journal title
Recueil des travaux chimiques des Pays-Bas → ACNP
ISSN journal
01650513
Volume
114
Issue
4-5
Year of publication
1995
Pages
184 - 194
Database
ISI
SICI code
0165-0513(1995)114:4-5<184:DIS.FD>2.0.ZU;2-7
Abstract
A range of rigid, architecturally complex diols derived from dispiroke tals have been synthesised. A bifunctional, C-2-symmetrical, chiral au xiliary derived from these dihydroxylated dispiroketals has been used to induce a high degree of asymmetry in Michael additions of cuprates to a variety of di-alpha,beta-unsaturated ester systems.