Objective: The author's goal was to shed light on the debate regarding
the mortality rate over time associated with anorexia nervosa. Method
: He conducted a meta-analytic study using weighted linear regression
to combine crude mortality proportions from 42 published studies to es
timate the mortality associated with anorexia nervosa over time. Resul
ts: The crude rate of mortality due to all causes of death for subject
s with anorexia nervosa in these studies was 5.9% (178 deaths in 3,006
subjects). The aggregate mortality rate was estimated to be 0.56% per
year, or approximately 5.6% per decade. Conclusions: The aggregate es
timated mortality rate for subjects with anorexia nervosa is substanti
ally greater than that reported for female psychiatric inpatients and
for the general population.