Objective: The authors studied the effects of the alpha(2)-receptor ag
onist clonidine on stuttering in children. Method: Using a double-blin
d crossover study, they gave placebo or 4 mu g/kg body weight per day
to 25 stuttering children who were 6-13 years old. Stuttering was meas
ured by counting the occurrences of four elementary speech difficultie
s and by asking parents and teachers to give an overall impression of
the amount of stuttering, as well as their impression of how troubleso
me the stuttering was to the children. Results: Clonidine did not impr
ove stuttering. Conclusions: Clonidine cannot be recommended as a usef
ul drug for treating children who stutter.