Influenza continues to be an important cause of preventable morbidity
and mortality. Although influenza vaccine is widely recommended for ol
der high-risk individuals, no studies have compared its use in differe
nt countries. We gathered information on influenza vaccine distributio
n in 18 developed countries for the period 1980-1992. During the 1980s
there was a greater than or equal to 10-fold difference in annual per
capita vaccine distribution among these countries, and in 1992 the di
fference was still more than 7-fold. Several countries demonstrated la
rge increases in vaccine use over the study period some showing substa
ntial increases in specific years. Thirteen of the 18 countries recomm
end influenza vaccination for all elderly persons and 11 countries pro
vide reimbursement for vaccination through national or social health i
nsurance. These countries tend to have higher levels of vaccine use. H
istorical, economic and political factors also affect vaccination prac
tices and policies, but their relationships to differences in vaccine
use between countries are not known. A better understanding of why the
use of influenza vaccine varies among countries will be important if
its protective benefits are to be fully realized.