CLOZAPINE FOR TARDIVE-DYSKINESIA IN ADOLESCENTS

Thousands of adolescents use neuroleptic drugs over extended periods o f time for a wide range of mental disorders. One of the most severe ad verse effects of neuroleptic drugs is tardive dyskinesia (TD), for whi ch no successful treatment is currently available. Clozapine is a know n atypical neuroleptic drug with few extrapyramidal side effects. It h as been suggested that clozapine may be beneficial for the treatment o f tardive dyskinesia in adolescents. However, the efficacy of the drug in adolescents is unknown. This report describes the beneficial effec t of clozapine on tardive dyskinesia in two adolescents with schizophr enia.