RELATIONSHIPS BETWEEN CARDIOVASCULAR AND IMMUNOLOGICAL CHANGES IN AN EXPERIMENTAL STRESS MODEL

Citation
Rj. Benschop et al., RELATIONSHIPS BETWEEN CARDIOVASCULAR AND IMMUNOLOGICAL CHANGES IN AN EXPERIMENTAL STRESS MODEL, Psychological medicine, 25(2), 1995, pp. 323-327
Citations number
29
Categorie Soggetti
Psycology, Clinical",Psychiatry,Psychology,Psychiatry
Journal title
ISSN journal
00332917
Volume
25
Issue
2
Year of publication
1995
Pages
323 - 327
Database
ISI
SICI code
0033-2917(1995)25:2<323:RBCAIC>2.0.ZU;2-H
Abstract
To investigate the relationships between cardiovascular variables (SEP , DBP, and HR) and circulating natural killer (NK) cell numbers, 70 ma le volunteers were subjected to a rest condition (N = 30) or a stressf ul laboratory task (N = 40). At baseline, no significant relationships could be demonstrated between the number of NK cells and the cardiova scular variables. Analysis of covariance showed that the stressor indu ced increases in the number of NK cells, SEP, DBP, and HR. Changes in NK cell numbers were highly correlated to changes in cardiovascular va riables in both the task and the no-task group. These results indicate that there is no relationship between the number of circulating NK ce lls and cardiovascular levels per se, but that changes in these variab les, either stress-induced or under rest conditions, are regulated by a common mechanism.