EFFICIENT SYNTHESIS OF DIASTEREOSELECTIVELY LABELED (3S)-[4-C-13]-L-VALINE, AND REGIOSELECTIVELY LABELED [3-(CH3)-C-13]-L-ISOLEUCINE HYDROCHLORIDES

Authors
HUMPHREY JM HART JA CHAMBERLIN AR
Citation
Jm. Humphrey et al., EFFICIENT SYNTHESIS OF DIASTEREOSELECTIVELY LABELED (3S)-[4-C-13]-L-VALINE, AND REGIOSELECTIVELY LABELED [3-(CH3)-C-13]-L-ISOLEUCINE HYDROCHLORIDES, Bioorganic & medicinal chemistry letters, 5(12), 1995, pp. 1315-1320
Citations number
38
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
12
Year of publication
1995
Pages
1315 - 1320
Database
ISI
SICI code
0960-894X(1995)5:12<1315:ESODL(>2.0.ZU;2-L
Abstract
Diastereoselectively labeled (3S)-[4-C-13]-L valine and regioselective ly labeled [3-(CH3)-C-13]-L-isoleucine hydrochlorides were synthesized in 54% and 62% respective overall yields from L-aspartic acid.