PROTEASES IN FAS-MEDIATED APOPTOSIS

Authors
ZHIVOTOVSKY B BURGESS DH SCHLEGEL J PORN MI VANAGS D ORRENIUS S
Citation
B. Zhivotovsky et al., PROTEASES IN FAS-MEDIATED APOPTOSIS, Journal of cellular biochemistry, 64(1), 1997, pp. 43-49
Citations number
54
Categorie Soggetti
Biology,"Cell Biology
Journal title
Journal of cellular biochemistry → ACNP
ISSN journal
07302312
Volume
64
Issue
1
Year of publication
1997
Pages
43 - 49
Database
ISI
SICI code
0730-2312(1997)64:1<43:PIFA>2.0.ZU;2-8
Abstract
Involvement of a unique family of cysteine proteases in the multistep apoptotic process has been documented. Cloning of several mammalian ge nes identifies some components of this cellular response. However, it is currently unclear which protease plays a role as a signal and/or ef fector of apoptosis. We summarize contributions to the data concerning proteases in Fas-mediated apoptosis. (C) 1997 Wiley-Liss, Inc.