Three groups of eight calves, naturally infected with gastrointestinal
nematodes acid artificially infected with Dictyocaulus viviparus were
used to evaluate the efficacy of moxidectin pour-on at dose rates of
0.35 mg/kg and 0.5 mg/kg bodyweight. With both doses the efficacy was
100 per cent against adult D viviparus, Trichostrongylus axei, Osterta
gia species and Nematodirus helvetianus. It was more than 99 per cent
against Ostertagia and Nematodirus species fourth stage larvae, A smal
l number of Cooperia species were found after treatment, and for this
parasite, the efficacy of moxidectin ranged from 97.6 per cent against
the larval stages to 98.8 per cent against the adults. No adverse rea
ctions to the moxidectin treatment were observed.