THE FIRST ENANTIOSELECTIVE SYNTHESIS OF ISOFLAVONOIDS - (R)-ISOFLAVANS AND (S)-ISOFLAVANS

Authors
VERSTEEG M BEZUIDENHOUDT BCB FERREIRA D SWART KJ
Citation
M. Versteeg et al., THE FIRST ENANTIOSELECTIVE SYNTHESIS OF ISOFLAVONOIDS - (R)-ISOFLAVANS AND (S)-ISOFLAVANS, Journal of the Chemical Society, Chemical Communications, (13), 1995, pp. 1317-1318
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
13
Year of publication
1995
Pages
1317 - 1318
Database
ISI
SICI code
0022-4936(1995):13<1317:TFESOI>2.0.ZU;2-O
Abstract
alpha-Benzylation of (+)- and (-)-N-phenylacetyl imidazolidinones with 2-O-methoxymethylbenzyl bromide, followed by reductive removal of the chiral auxiliary and cyclization, leads to isoflavans in excellent en antiomeric excess and yield.