Cdc. Madruga et al., HALOACETYLATED ENOL ETHERS .4. SYNTHESIS OF 4-TRIHALOMETHYL-2-METHYLTHIOPYRIMIDINES, Journal of heterocyclic chemistry, 32(3), 1995, pp. 735-738
The synthesis of a series of 5- and 6-substituted 4-trihalomethyl-2-me
thylthiopyrimidines, prepared from the cyclocondensation reaction of b
eta-alkoxyvinyl tri[fluoro]chloromethyl ketones with 2-methyl-2-thiops
eudourea sulfate, are reported. A systematic study to find the best re
action conditions were carried out.