SYNTHESIS 1,2,3-TRIAZOLO[1,5-A]PYRIDINE ESTER DERIVATIVES

Authors
LATHAM EJ STANFORTH SP
Citation
Ej. Latham et Sp. Stanforth, SYNTHESIS 1,2,3-TRIAZOLO[1,5-A]PYRIDINE ESTER DERIVATIVES, Journal of heterocyclic chemistry, 32(3), 1995, pp. 787-789
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
32
Issue
3
Year of publication
1995
Pages
787 - 789
Database
ISI
SICI code
0022-152X(1995)32:3<787:S1ED>2.0.ZU;2-7
Abstract
Lithiation of 1,2,3-triazolo[1,5-a]pyridines 4b and 4c with Lithium di isopropylamide (LDA) gave the corresponding lithio derivatives 5b and 5c from which esters 6b and 6c were obtained by treatment with carbon dioxide and then dimethyl sulfate. Lithio derivatives 5a-5c reacted wi th DMF giving aldehydes 7a-7c. Esters 9a-9c were prepared from aldehyd es 7a-7c and carbomethoxymethylenetriphenylphosphorane.