CONVENIENT SYNTHESIS OF -(T-BUTYLOXYCARBONYLAMINO)-2'-PHENYLETHYL]OXIRANE, A VERSATILE INTERMEDIATE FOR THE PREPARATION OF HYDROXYETHYLAMINE BASED HIV PROTEASE INHIBITORS

Authors
GREEN BE CHEN XQ NORBECK DW KEMPF DJ
Citation
Be. Green et al., CONVENIENT SYNTHESIS OF -(T-BUTYLOXYCARBONYLAMINO)-2'-PHENYLETHYL]OXIRANE, A VERSATILE INTERMEDIATE FOR THE PREPARATION OF HYDROXYETHYLAMINE BASED HIV PROTEASE INHIBITORS, Synlett, (6), 1995, pp. 613-614
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
6
Year of publication
1995
Pages
613 - 614
Database
ISI
SICI code
0936-5214(1995):6<613:CSO->2.0.ZU;2-S
Abstract
A concise, stereocontrolled synthesis of N-protected (1S,1'S)-alpha-am inoepoxides, important intermediates for the preparation of hydroxyeth ylamine dipeptide isosteres, beginning with alpha-aminoesters is descr ibed.