M. Dacasto et U. Cocuzza, EFFICACY OF IVERMECTIN IN REDUCING GASTROINTESTINAL NEMATODE FECAL EGG COUNTS IN GOATS IN BURUNDI, Preventive veterinary medicine, 23(3-4), 1995, pp. 173-178
Cross-bred goats in Burundi infested with gastrointestinal nematodes w
ere submitted to fecal investigations and injected subcutaneously with
ivermectin. In Experiment 1, goats were treated with 200 mu g kg(-1)
bw ivermectin. In Experiment 2, animals were administered twice that d
ose. In Experiment 3, goats suspected to be resistant to other anthelm
intics were treated with 200 mu g kg(-1) bw ivermectin. In Experiment
4, two doses of the same strength were injected with an interval of 7
days. Results demonstrate that 200 mu g kg(-1) bw ivermectin is effect
ive for the control of gastrointestinal nematodes of goats in Burundi;
this dosage is also effective against nematodes suspected to be resis
tant to other anthelmintics. The administration of 400 mu g kg(-1) bw
did not induce greater or more prolonged effectiveness percentages. Th
e supposed decrease of ivermectin's residual activity on Day 28 might
be avoided by administering two doses with an interval of 7 days. No a
dverse effects were observed in treated animals.