Background: Persistent telangiectases are a feature of neonatal lupus
erythematosus (NLE) but have generally been noted in areas of prior in
flammatory disease. The occurrence of vascular macules and papules at
sites without preceding dermatitis has not been reported in NLE. Objec
tive: Our purpose was to emphasize a previously unidentified aspect of
cutaneous NLE: the presence of angiomatous or matlike telangiectases
in sites without antecedent or concurrent dermatitis. Methods: We desc
ribe seven patients in which telangiectatic macules or angiomatous pap
ules were primary or early features of NLE. Results: Five infants lack
ed a history of preceding or concurrent inflammatory lesions at sites
of telangiectasia development. In four infants findings included vulva
r or inguinal angiomatous papules. Conclusion: Telangiectases may be a
presenting feature of NLE, can be found in sun-protected sites, and m
ay occur independent of ''lupus dermatitis.''