BACKGROUND: Closure of the abdominal wall in the face of fascial necro
sis or massive intestinal edema remains a difficult problem with frequ
ent complications, Prior studies have addressed both the utility and t
he pitfalls of placing polypropylene mesh in this setting. METHODS: We
performed a retrospective evaluation of our experience with polypropy
lene mesh in traumatic and nontraumatic difficult abdominal closures,
Timing of mesh placement and removal relative to the initial operation
were recorded, as were abdominal complications, number of operative p
rocedures, and type of ultimate abdominal closure, RESULTS: Between 19
88 and 1993, polypropylene mesh was placed in 26 critically ill or inj
ured patients requiring celiotomy, of whom 23 survived more than 3 wee
ks, Ultimate wound management was delayed mesh removal and primary clo
sure (17%), myocutaneous flap coverage over mesh (4%), split-thickness
skin grafting to the granulating wound (35%), or closure by secondary
intention over mesh (43%), Split-thickness skin grafting and closure
by secondary intention resulted in enterocutaneous fistulas in 50% and
40% of cases, respectively, Full-thickness closure with or without me
sh removal resulted in no fistulas, CONCLUSION: Mesh provided adequate
fascial closure, even with gross wound contamination. Coverage of pol
ypropylene mesh by secondary intention or split-thickness skin graftin
g resulted in unacceptably high rates of fistulous complications, and
this procedure should be replaced by either mesh removal or full-thick
ness coverage,