ANALYSIS OF TISSUE ORGANIZATION BY MICROINJECTION OF FOLLISTATIN INTOEARLY XENOPUS-LAEVIS EMBRYOS

Authors
LAU CL
Citation
Cl. Lau, ANALYSIS OF TISSUE ORGANIZATION BY MICROINJECTION OF FOLLISTATIN INTOEARLY XENOPUS-LAEVIS EMBRYOS, Tissue & cell, 27(3), 1995, pp. 331-337
Citations number
24
Categorie Soggetti
Cell Biology
Journal title
Tissue & cell → ACNP
ISSN journal
00408166
Volume
27
Issue
3
Year of publication
1995
Pages
331 - 337
Database
ISI
SICI code
0040-8166(1995)27:3<331:AOTOBM>2.0.ZU;2-4
Abstract
Xenopus laevis embryos injected with follistatin developed abnormally with enlarged anterior structures and defective tails. Histological se ctions reveal that these follistatin treated embryos contain large amo unt of notochordal tissue that fails to elongate. Embryonic responses to follistatin are dose and stage specific. These results suggested th at follistatin contributes to body axis formation, with its most visib le effect on notochord formation.