Renal aspergillomas have been reported only rarel., We report a case o
f Aspergillus flavus colonization of the renal pelvis and upper ureter
of a patient with concomitant urinary schistosomiasis. The diagnosis
was based on the demonstration of characteristic hyphal elements on di
rect microscopy and isolation of the fungus in culture. The patient wa
s successfully treated with liposomal amphotericin B. This case emphas
izes the importance of direct microscopic examination of urine specime
ns for prompt diagnosis of fungal infections of the urogenital system.
Renal aspergilloma should be considered in the differential diagnosis
of filling defects of the urinary tract, especially in patients who a
re immunocompromised.