Rp. Hsung et al., THIOPHENOL PROTECTING GROUPS FOR THE PALLADIUM-CATALYZED HECK REACTION - EFFICIENT SYNTHESES OF CONJUGATED ARYLTHIOLS, Tetrahedron letters, 36(26), 1995, pp. 4525-4528
A variety of S-thiophenol protecting groups have been evaluated for th
e Heck reaction. Of these, the S-acetyl group appears to be the best s
uited for facile removal under mild conditions to provide the correspo
nding free thiols in high yields.