DETERMINATION OF THE GENE ORDER OF THE 3 LOCI CD2, NGFB, AND NRAS AT HUMAN-CHROMOSOME BAND 1P13 AND REFINEMENT OF THEIR LOCALIZATION AT THESUBBAND LEVEL BY FLUORESCENCE IN-SITU HYBRIDIZATION

Authors
MITCHELL ELD JONES D WHITE GRM VARLEY JM KOREF MFS
Citation
Eld. Mitchell et al., DETERMINATION OF THE GENE ORDER OF THE 3 LOCI CD2, NGFB, AND NRAS AT HUMAN-CHROMOSOME BAND 1P13 AND REFINEMENT OF THEIR LOCALIZATION AT THESUBBAND LEVEL BY FLUORESCENCE IN-SITU HYBRIDIZATION, Cytogenetics and cell genetics, 70(3-4), 1995, pp. 183-185
Citations number
8
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
70
Issue
3-4
Year of publication
1995
Pages
183 - 185
Database
ISI
SICI code
0301-0171(1995)70:3-4<183:DOTGOO>2.0.ZU;2-0
Abstract
The three loci NRAS, NGFB, and CD2 map to human chromosome band 1p13. Using fluorescence in situ hybridisation (FISH) to simultaneously DAPI -banded metaphase chromosomes, we have further refined the localisatio n of these three genes to specific subbands. NRAS localises to subband 1p13.2 and CD2 and NGFB to 1p13.1. Also, with the use of multicolour FISH, we have determined the order and orientation of the three loci i n relation to the centromere. The order is cen-CD2-NGFB-NRAS.