NEUROPSYCHIATRIC MANIFESTATIONS OF SYSTEMIC LUPUS-ERYTHEMATOSUS

The authors critically review the literature describing the varied neu ropsychiatric syndromes associated with systemic lupus erythematosus ( SLE). Factors that have complicated the identification and treatment o f affective, behavioral, and cognitive disturbances in these patents a re identified, and the utility of various diagnostic interventions is examined. Finally, the authors outline the role of the consultation-li aison psychiatrist in the clinical management of the SLE patient with neuropsychiatric disturbances.