Background: The data regarding goitre prevalence in Germany is based o
n calculation arising out of dissimilar studies conducted among inhomo
genous study groups. The aim of our study was to collect data towards
prevalence of goitre, thyroid size and structure through a prospective
nationwide survey conducted using identical examination methods and s
tudy protocol. Patients and Method: A total number of 6815 subjects be
longing to various age groups and spread over 32 regions in Germany pa
rticipated in our thyroid ultrasound study conducted with a 7.5 MHz tr
ansducter. Informations regarding nutrition, use of iodised table salt
and iodine containing medicine and/or substances were collected throu
gh a questionnaire. The volumetry and age related normal values were f
ollowed as per the guidelines set by Deutsche Gesellschaft fur Endokri
nologie. Results: Enlarged thyroid was seen in 50% of 18 to 70 year ag
e soup, 52% of 11 to 17 year age group and in 21% of children up to 10
years. Focal lesions were detected in 2,5% of subjects below 18 years
and in 30% of women and 21% of men over 18 years. A positive correlat
ion between age, thyroid volume and number of thyroid nodules was seen
. Up to 83% of the examined subjects admitted to using iodised table s
alt. Children consuming iodised salt were found to have smaller thyroi
d glands. No correlation was found between the consumption of iodised
salt and thyroid size in the adolescent age group and young adults. Co
nclusion: The prevalence of goitre in Germany is higher than it has be
en reported. The study underlines the insufficiency of the present goi
tre prophylaxis. Only an iodine prophylaxis (table salt, food products
, fodder) backed by legislative measures can bring about a real breakt
hrough.