STUDIES ON THE INHIBITORY EFFECTS OF CAFFEOYLQUINIC ACIDS ON MONOCYTEMIGRATION AND SUPEROXIDE ION PRODUCTION

Authors
PELUSO G DEFEO V DESIMONE F BRESCIANO E VUOTTO ML
Citation
G. Peluso et al., STUDIES ON THE INHIBITORY EFFECTS OF CAFFEOYLQUINIC ACIDS ON MONOCYTEMIGRATION AND SUPEROXIDE ION PRODUCTION, Journal of natural products, 58(5), 1995, pp. 639-646
Citations number
20
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
58
Issue
5
Year of publication
1995
Pages
639 - 646
Database
ISI
SICI code
0163-3864(1995)58:5<639:SOTIEO>2.0.ZU;2-5
Abstract
Three caffeoylquinic acids, isolated from the Peruvian plants Tessaria integrifolia and Mikania cordifolia that are used medicinally as anti -inflammatory agents, were tested for their activities on monocyte mig ration and superoxide anion production. 3,5-Di-O-caffeoylquinic and 4, 5-di-O-caffeoylquinic acids exhibited an appreciable anti-inflammarory activity in vitro, while the tricaffeoyl derivative was inactive.