NOVEL WITHANOLIDES FROM JABOROSA-SATIVA

Authors
BONETTO GM GIL RR OBERTI JC VELEIRO AS BURTON G
Citation
Gm. Bonetto et al., NOVEL WITHANOLIDES FROM JABOROSA-SATIVA, Journal of natural products, 58(5), 1995, pp. 705-711
Citations number
24
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
58
Issue
5
Year of publication
1995
Pages
705 - 711
Database
ISI
SICI code
0163-3864(1995)58:5<705:NWFJ>2.0.ZU;2-L
Abstract
Four new withanolides [1-4] have been isolated from the aerial parts o f Jaborosa sativa. Jaborosalactones R [1], S [2], and T [3] contain a hemiketal (or ketal) ring formed between a 21-hydroxyl and a 12-ketone and the characteristic delta-lactone side-chain of the withanolides. Jaborosalactone U [4] possesses an epoxy-gamma-lactone side-chain and was identified as the 24,25-epoxy analogue of trechonolide A [5].