N-METHYL-N-(TRIETHOXYSILYLMETHYL) AND N-METHYL-N-(SILATRAN-1-YLMETHYL) SUBSTITUTED GLYCINE AND ALANINE

Organosilicon derivatives of glycine, alpha- and beta-alanine, and alp ha-methylalanine were prepared by the reaction of methyl esters of alp ha- and beta-halocarboxylic acids with N-methyl-aminomethyltriethoxysi lane in the presence of triethylamine. The compounds synthesized were converted into the corresponding N-silatran-1-ylmethyl derivatives. Tr imethyl-silyliodoacetate reacts with N-methylaminomethyltrietoxysilane to give hoxy-4-methyl-1-oxa-4-aza-2-silacyclohexane-6-one. Its reacti on with triethanolamine leads to N-methyl-N-(silatran-1-ylmethyl)glyci ne.