Synthesis of new 6-(4-chlorophenyl)-5,6,7,8-tetrahydroindolizines was
achieved starting from 4-amino-3-(4-chlorophenyl)butyric acid (Baclofe
n). The chemical pathway, involving a Clauson-Kaas reaction and a subs
equent cyclization, led to an iminium salt whose reactivity was studie
d.