E. Windeisen et al., NEW TYPES OF BIORELEVANT ALPHA-FUNCTIONAL CARBOXYLIC-ACIDS AND THEIR APPLICATION FOR PEPTIDE MODIFICATION, Amino acids, 8(4), 1995, pp. 397-400
New methodology for the preparation of L-isoserine and its incorporati
on into N- and C-terminal position of peptides is described. Furthermo
re, the new protective group strategy allows regioselective functional
group manipulation in multifunctional amino acids like serine and iso
serine.