M. Tendler et al., VACCINATION AGAINST SCHISTOSOMIASIS AND FASCIOLIASIS WITH THE NEW RECOMBINANT ANTIGEN SM14 - POTENTIAL BASIS OF A MULTIVALENT ANTI-HELMINTHVACCINE, Memorias do Instituto Oswaldo Cruz, 90(2), 1995, pp. 255-256
Molecular cloning of components of protective antigenic preparations h
ave suggested that related parasite fatty acid binding proteins could
form the basis of the well documented protective, immune cross reactiv
ity between the parasitic trematode worms Fasciola hepatica and Schist
osoma mansoni. We have now confirmed the cross protective potential of
parasite fatty acid binding proteins and suggest that it may be possi
ble to produce a single vaccine that would be effective against at lea
st two parasites, F. hepatica and S. mansoni of veterinary and human i
mportance respectively.