VACCINATION AGAINST SCHISTOSOMIASIS AND FASCIOLIASIS WITH THE NEW RECOMBINANT ANTIGEN SM14 - POTENTIAL BASIS OF A MULTIVALENT ANTI-HELMINTHVACCINE

Authors
TENDLER M VILAR MM BRITO CA FREIRE NMS KATZ N SIMPSON A
Citation
M. Tendler et al., VACCINATION AGAINST SCHISTOSOMIASIS AND FASCIOLIASIS WITH THE NEW RECOMBINANT ANTIGEN SM14 - POTENTIAL BASIS OF A MULTIVALENT ANTI-HELMINTHVACCINE, Memorias do Instituto Oswaldo Cruz, 90(2), 1995, pp. 255-256
Citations number
6
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Memorias do Instituto Oswaldo Cruz → ACNP
ISSN journal
00740276
Volume
90
Issue
2
Year of publication
1995
Pages
255 - 256
Database
ISI
SICI code
0074-0276(1995)90:2<255:VASAFW>2.0.ZU;2-H
Abstract
Molecular cloning of components of protective antigenic preparations h ave suggested that related parasite fatty acid binding proteins could form the basis of the well documented protective, immune cross reactiv ity between the parasitic trematode worms Fasciola hepatica and Schist osoma mansoni. We have now confirmed the cross protective potential of parasite fatty acid binding proteins and suggest that it may be possi ble to produce a single vaccine that would be effective against at lea st two parasites, F. hepatica and S. mansoni of veterinary and human i mportance respectively.