The early time of Analytical Chemistry in Romania is presented. Starti
ng from 1920, the famous schools of chemical analysis in the Universit
y of Cluj, Bucharest and Iassy were established. As an example, the te
am headed by Professor G. Spacu introduced the use of complex compound
s as reagents in analytical chemistry. In this way many macro and micr
o gravimetric methods for elemental determination were proposed.