DIFFERENTIAL IMPACT ON PREGNANCY RATE OF SELECTIVE SALPINGOGRAPHY TUBAL CATHETERIZATION AND WIRE-GUIDE RECANALIZATION IN THE TREATMENT OF PROXIMAL FALLOPIAN-TUBE OBSTRUCTION
R. Woolcott et al., DIFFERENTIAL IMPACT ON PREGNANCY RATE OF SELECTIVE SALPINGOGRAPHY TUBAL CATHETERIZATION AND WIRE-GUIDE RECANALIZATION IN THE TREATMENT OF PROXIMAL FALLOPIAN-TUBE OBSTRUCTION, Human reproduction, 10(6), 1995, pp. 1423-1426
A total of 66 patients with proximal Fallopian tube (113 tubes) obstru
ction, as diagnosed by both laparoscopy and hysterosalpingogram, were
each subjected to a transcervical recanalization procedure sequentiall
y using selective salpingography followed, if necessary, by tubal cath
eterization with a soft Teflon 2-French catheter and finally, if neede
d, wire-guide cannulation, Each procedure was terminated once patency
had been achieved without recourse to the next technique, Bilateral ob
struction was present in 47 patients and unilateral in 19 patients, Pa
tency was achieved in 39 (34.5%) Fallopian tubes by selective salpingo
graphy alone, in 52 (46.0%) by tubal catheterization and in 10 (8.9%)
by wire guide, with 12 (10.6%) tubes remaining obstructed, Pregnancy o
ccurred in 24 (36.4%) patients without recourse to other treatment (me
an follow-up, 17 months), Where patency was achieved (59 patients), 19
out of 43 (44.1%) of those treated for bilateral obstruction and five
out of 16 (31.3%) of those treated for unilateral obstruction achieve
d a pregnancy, Pregnancy occurred in six out of 22 patients (27.3%) wh
ere selective salpingography was used to produce tubal patency, in 17
out of 30 patients (56.7%) where tubal catheterization was used and in
one out of seven (14.3%) where a wire guide was used, which was an ec
topic pregnancy, The difference between the ongoing pregnancy rates fo
llowing tubal catheterization (50.0%) and wire-guide cannulation (0.0%
) was significant (P = 0.033), While wire-guide cannulation is the mos
t effective method used to achieve tubal patency, these results indica
te that when it is truly necessary, as opposed to electively used by c
linicians, the prognosis with regard to pregnancy is poor and alternat
ive therapy such as microsurgery or in-vitro fertilization should be c
onsidered early.