ETIOLOGY OF AGE-ASSOCIATED ANEUPLOIDY - A MECHANISM-BASED ON THE FREE-RADICAL THEORY OF AGING

Authors
TARIN JJ
Citation
Jj. Tarin, ETIOLOGY OF AGE-ASSOCIATED ANEUPLOIDY - A MECHANISM-BASED ON THE FREE-RADICAL THEORY OF AGING, Human reproduction, 10(6), 1995, pp. 1563-1565
Citations number
25
Categorie Soggetti
Reproductive Biology
Journal title
Human reproduction → ACNP
ISSN journal
02681161
Volume
10
Issue
6
Year of publication
1995
Pages
1563 - 1565
Database
ISI
SICI code
0268-1161(1995)10:6<1563:EOAA-A>2.0.ZU;2-Y
Abstract
A general model is put forward to explain the mechanism by which age-a ssociated aneuploidies are produced. This is based on the free radical theory of ageing, which assumes a rise in oxidative stress with age. It is proposed that determination of indicators of oxidative stress in oocytes from various sources Could be a first step in the testing of this hypothesis.