The coexistence of different clinical syndromes due to atherosclerosis
in different organs is not rare and emphasizes the diffuse nature of
this vascular process. Although renovascular disease may cause hyperte
nsion and/or renal insufficiency, it may also occur in the absence of
the usual clinical markers that suggest renovascular hypertension. We
report a patient with stable coronary anatomy who presented with cresc
endo angina pectoris. Diagnosis of renovascular hypertension was made
by screening renal angiography at the time of the cardiac catheterizat
ion. Renal artery stenting resulted in stabilization of the coronary s
yndrome and obviated the need for further coronary intervention. To ou
r knowledge, this is the first case of renovascular hypertension preci
pitating an unstable coronary syndrome in a patient with documented st
able coronary anatomy. Review of the literature supports that patients
undergoing cardiac catheterization are a high risk population for ren
ovascular disease, particularly in the presence of other predictive fa
ctors such as documented coronary artery disease, older age, female ge
nder, congestive heart failure, peripheral vascular disease, renal ins
ufficiency, and smoking. Firm recommendations for routine screening re
nal angiography in patients undergoing peripheral or coronary angiogra
phy will need further studies. (C) 1995 Wiley-Liss, Inc.