POLIOMYELITIS PREVENTION - RECOMMENDATIONS FOR USE OF INACTIVATED POLIOVIRUS VACCINE AND LIVE ORAL POLIOVIRUS VACCINE

A change in the recommendations for routine immunization of children i s indicated because of the reduced risk of exposure to wild-type polio viruses and the continued occurrence of vaccine-associated paralytic poliomyelitis after oral polio vaccine (OPV). All children should rece ive four doses of vaccine before the child enters school. Regimens of sequential inactivated polio vaccine (IPV) and OPV, IPV only, or OPV o nly are acceptable. Each regimen has advantages and disadvantages. In special circumstances, one of the regimens is preferred or recommended . Because logistical problems with the current childhood immunization schedule may make these new recommendations difficult to implement imm ediately, their adoption likely will be gradual. Nevertheless, assumin g continued progress toward global eradication and the development of new combination products, the routine use of an IPV-only regimen is li kely to become desirable and feasible in future years.