Background. Resection of hepatic tumors located near the confluence of
the hepatic vein or invading the inferior vena cava has become techni
cally feasible and relatively safe by using venovenous bypass. However
, some technical problems remain to be solved. Methods. We performed t
hree cases of hepatic resection under extracorporeal circulation combi
ned with hypothermic perfusion. Results. An unexpected hemorrhage was
observed in all three cases for different causes. The patient of case
2 died of liver failure developed from fatty liver. Bile duct stenosis
was observed in cases 1 and 3. Conclusions. Although hepatectomy unde
r total vascular exclusion by use of Biopump is now considered a safe
procedure, attention should be paid when this procedure is performed b
ecause some technical problems still remain.