C-13 NMR INVESTIGATIONS OF 3 FLUORINATED STEROIDS

High-resolution carbon-13 NMR spectra were obtained for three solid fl uorinated steroids. Assignments were carried out using several approac hes, including two-dimensional spectra of the compounds in solution. S olid-state and solution-state chemical shifts are compared. Signals fr om one of the fluorine-containing carbons in each compound show the ef fect of interplay between shielding, dipolar and indirect scaler (J) c oupling tensors. One sample is found to be a mixture of two polymorphi c forms.