G. Maina et al., TYPE-I AND TYPE-II SCHIZOPHRENIA - RELATIONS BETWEEN TONIC ELECTRODERMAL ACTIVITY AND CLINICAL RATINGS BEFORE AND AFTER HALOPERIDOL TREATMENT, Psychiatry research, 57(1), 1995, pp. 49-56
To test the hypothesis that schizophrenic patients with positive vs. n
egative symptoms show different tonic electrodermal patterns, 26 patie
nts with Type I schizophrenia and 19 patients with Type II schizophren
ia were evaluated before and after 2 weeks of haloperidol treatment (s
tandard daily dose = 4.5 mg). Clinical assessments were made with the
Brief Psychiatric Rating Scale, the Scale for the Assessment of Positi
ve Symptoms, and the Scale for the Assessment of Negative Symptoms. Sk
in conductance level (SCL) and spontaneous fluctuations (SF) frequency
were recorded for each patient. Before treatment, Type I patients sho
wed higher SCL and SF compared with Type II patients; after treatment,
a significative decrease of clinical and psychophysiological variable
s was found only in Type I patients.