W. Dong et al., REGULATION OF CELLULASE SYNTHESIS IN MYCELIAL FUNGI - PARTICIPATION OF ATP AND CYCLIC-AMP, Biotechnology letters, 17(6), 1995, pp. 593-598
ATP and cAMP in 4 strains of mycelial fungi were determined by lucifer
in-luciferase system and HPLC respectively. Cellulase synthesis was su
bject to the dual control of ATP and cAMP. No matter what carbon sours
e was used, cellulase synthesis was repressed if intracellular ATP con
centration was over 10(-7)mg/ml. Exogenous cAMP could increase cellula
se synthesis under depression conditions.