Gr. Dhaens et Pj. Rutgeerts, POSTOPERATIVE RECURRENCE OF CROHNS-DISEASE - PATHOGENESIS AND PREVENTION, Acta Gastro-Enterologica Belgica, 57(5-6), 1994, pp. 311-313
Postoperative recurrence of Crohn's disease is very common and almost
invariably appears at the ileal side of the ileocolonic anastomosis. L
uminal factors are believed to play an essential role in triggering th
e earliest inflammatory events. The characteristics of recurrent disea
se are often very similar to those of the original presentation before
surgery. Several 5-ASA preparations as well as antibiotics such as me
tronidazole have been shown to affect incidence and/or severity of rec
urrence of Crohn's disease.