PURPOSE/METHODS: To evaluate the role of initial visual acuity as a fa
ctor for progressive loss of vision or progression to a full thickness
macular hole in eyes with stage I macular holes (tractional foveal de
tachment without dehiscence). The study population included 35 patient
s with stage I macular holes with best corrected visual acuity of 20/2
5 to 20/80 in one eye, and a full-thickness macular hole in the fellow
eye. RESULTS/CONCLUSIONS: Eyes with stage I macular holes with best c
orrected visual acuity between 20/50 and 20/80 had a 66% (ten of 15 ey
es) rate of progression to full-thickness macular hole, whereas eyes w
ith best corrected visual acuity of between 20/25 and 20/40 had a 30%
(six of 20 eyes) risk of progression to full thickness macular hole. T
he risk of progression to macular hole is significantly higher in eyes
with stage I macular holes with best-corrected visual acuity of 20/50
or worse (P = .03).