An easy accessible dendrimer monomer 3,5-bis(2-tert-butyloxycarbonyl a
minoethoxy) benzoic acid methyl ester 1 was designed. The monomer was
converted to both the ''surface'' and ''braching'' monomer in a versat
ile synthesis of a novel amino acid based dendrimer by the covergent m
ethod, using the well established and high-yielding BOP-peptide coupli
ng method. (C) 1997, Elsevier Science Ltd. All rights reserved.