STERICALLY CROWDED HETEROCYCLES .2. CONFORMATIONAL STRUCTURE OF DIPHENYL-3-OXOPROPENYL]-IMIDAZO[1,2-ALPHA]PYRIDINE AND RELATED-COMPOUNDS

Authors
BOHM S KUBIK R HRADILEK M NEMECEK J HUSAK M KRATOCHVIL B KUTHAN J
Citation
S. Bohm et al., STERICALLY CROWDED HETEROCYCLES .2. CONFORMATIONAL STRUCTURE OF DIPHENYL-3-OXOPROPENYL]-IMIDAZO[1,2-ALPHA]PYRIDINE AND RELATED-COMPOUNDS, Collection of Czechoslovak Chemical Communications, 60(1), 1995, pp. 115-126
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
60
Issue
1
Year of publication
1995
Pages
115 - 126
Database
ISI
SICI code
0010-0765(1995)60:1<115:SCH.CS>2.0.ZU;2-2
Abstract
Conformational behaviour of -1,3-diphenyl-3-oxopropenyl]imidazo[1,2-a] pyridine I is studied using a molecular isoenergy map calculated by th e PM3 method. A predicted potency of this approach is discussed with r espect to the experimental solid state structures of related compounds I - IV. Complete X-ray structures of 7-methyl derivative IV and 11-ph enyl derivative V are reported.