T. Herchline et S. Gros, IMPLEMENTATION OF CONSENSUS GUIDELINES FOR THE FOLLOW-UP OF POSITIVE BLOOD CULTURES, Infection control and hospital epidemiology, 18(1), 1997, pp. 38-41
OBJECTIVE: Assess the effect and use of resources associated with impl
ementation of a program for the systematic follow-up of positive blood
cultures. DESIGN: Prospective epidemiologic study. SETTING: Tertiary-
care military medical center. INTERVENTION: All positive blood culture
s (BC) were reported via E-mail to an infectious disease specialist as
soon as growth was noted. This individual reviewed all Gram stains, c
linical data, and antibiotic information on these patients. RESULTS: F
rom June 26, 1994, through January 25, 1995, there were 3,121 BCs draw
n, of which 199 (6.4%) were positive from 145 episodes. Sixty-three ep
isodes involved probable contaminants, and 82 episodes were considered
true bacteremias. Six patients with true bacteremia died, two were tr
ansferred, and three were discharged within 24 hours of drawing the po
sitive BC. Of the remaining 71 true bacteremias, 9 patients were on in
adequate empiric therapy, as judged by the final organism susceptibili
ties. Changes in empiric therapy were recommended for five of the nine
episodes and were implemented by the primary physicians in each case,
Each of the changes resulted in improved coverage (as judged by the f
inal identification and susceptibilities). CONCLUSIONS: This program h
as improved the quality of care at Keesler Medical Center at the cost
of one additional hour of consultant time per week.