MALIGNANT FIBROUS HISTIOCYTOMA OF THE UTERUS - SOME IMMUNOHISTOCHEMICAL AND ULTRASTRUCTURAL OBSERVATIONS

Hysterectomy was performed in a 64-year-old woman because of a uterine malignant tumor which extensively involved both the endometrium and t he myometrium. Histological examination revealed a malignant fibrous h istiocytoma (MFH) of the pleomorphic-storiform type. The presence of e pithelial or heterologous mesenchymal tumor components or cells of smo oth muscle derivation was ruled out by immunohistochemistry and electr on microscopy. The patient developed pulmonary metastases and died six months after surgery. MFH is a rare primary tumor of the uterus, but it should be considered in cases of malignant mesenchymal tumors witho ut heterologous elements or signs of smooth muscle derivation.