Hemofiltration creates the best conditions for toxin removal and cardi
ovascular stability in the treatment of chronic renal failure patients
. The increase in hematocrit due to erythropoietin, the blood flow rat
e and the necessary volume of substitution fluid limit the post- or th
e predilution hemofiltration. The technical progress made now offers t
he possibility to routinely and safely treat patients with pre-/postdi
lution hemofiltration. When adjusting the substitution flow rate to th
e blood flow rate, small-molecule clearances are higher than those in
hemodialysis and are close to those in hemodiafiltration.