Computerized analysis and topographical mapping were performed on the
EEGs of 28 migraine patients (17 without and II with typical aura) and
an age and sex-matched control group of 28 subjects. Traditional visu
al EEG analysis revealed only a slight diffuse slowing of theta band i
n eight patients (28.6%), and computerized analysis revealed significa
nt changes in eleven (39.3%). The most frequently altered parameters w
ere an increase in the relative power of the slow bands and/or a decre
ase in that of alpha band, These variations appeared to be particularl
y significant in the posterior regions, No significant inter-hemispher
e asymmetry was revealed. Comparisons between the patient and control
groups showed that the only statistically significant difference was a
bilateral increase in theta power in the parieto-occipital regions of
the patients. We conclude that the role of topographical EEG mapping
in the clinical diagnosis of migraine is still limited.