ONTOGENY OF THYMOCYTES IN SEA BASS DICENTRARCHUS-LABRAX - STUDIES WITH MONOCLONAL-ANTIBODIES

The monoclonal antibody DLT15 directed against thymocytes of the sea b ass Dicentrarchus labrax specifically recognised an antigen determinan t(s) expressed during development of thymic lymphoid cells. While immu noreaction is excluded from lymphoblast-like cells present in the thym ic anlage, it was first detected one month post-haching in thymocytes. Thereafter, a marked increase in number of immunoreactive cells occur red mostly in the outer region of the thymus. This study aimed to anal yse the chronology and some features of thymocyte differentiation.