AGGRESSIVE BONE DESTRUCTION IN ACUTE MEGAKARYOCYTIC LEUKEMIA - A RAREPRESENTATION

Acute megakaryocytic leukemia (AMKL) is a rare subtype of acute myeloi d leukemia which is more common in children. Although the bone changes in leukemia are well documented, there are only a few reports of the AMKL subtype. We present an exceptional case of a young girl with very aggressive AMKL, who demonstrated symmetrical destructive lesions of the long bones characteristic of this disease. Lytic lesions of the sk ull and jaws were also present, and these have not been previously des cribed in AMKL.