Stroke is unique among neurological diseases since it has a high incid
ence rate, severe burden of illness, high economic cost, and it may be
preventable [1]. Described here is a system for screening the cerebra
l and vascular status of individuals to detect the initial stages of v
ascular disorders. The computer based polygraphic system (CERBERUS) qu
estions subjects about risk factors, stresses, neurologic symptoms and
monitors impedance pulse waves of the head and extremities, EEG, and
EGG. The system has been tested in 691 cases. Doppler control studies
were carried out on approximately 300 of these cases. Additional somat
ic measures and psychological tests related to stroke risk factors wer
e carried out for wide biological basis of possible correlation of CER
BERUS data base. The high incidence of cerebrovascular disturbance was
established by CERBERUS data, further confirmed by additional data ga
thered, and moreover was compared by traditional medical records. The
polygraphic system is more sensitive at detecting physiological asymme
tries of blood flow than even a Doppler measurements. This suggests th
at it may be a significantly improved means for the differential diagn
osis of neurological disease and the screening of subjects for arterio
sclerosis, transient ischemic attack and stroke prevention to be offer
ed at the lowest level of medical service.