De. Williamson et al., STRESSFUL LIFE EVENTS AND EEG SLEEP IN DEPRESSED AND NORMAL CONTROL ADOLESCENTS, Biological psychiatry, 37(12), 1995, pp. 859-865
EEG sleep measures in 35 depressed and 33 normal control adolescents w
ere examined in relation to stressful life events occurring in the yea
r before sleep studies, There was a significant interaction between st
ressful life events and diagnostic status for REM latency and total RE
M time, In the normal controls, the presence of stressful life events
was significantly associated with reduced REM latency and increased to
tal REM time. Among the depressed adolescents, there were no significa
nt effects of stressful life events on REM latency or total REM time,
The depressed adolescents with no stressful life events (n = 9) had si
gnificantly lower REM latency values compared to normal control adoles
cents with no stressful life events (n = 13) (61.7 +/- 50.0 vs. 132.1
+/- 79.0, p less than or equal to.01). It appears that stressful life
events influence at least some measures of adolescent sleep and should
be considered in future controlled studies aimed at understanding sle
ep changes in adolescent depression.