PLASMA-LEVELS OF 8-METHOXYPSORALEN AFTER BATH-PUVA FOR PSORIASIS - RELATIONSHIP TO DISEASE SEVERITY

Authors
GOMEZ MI AZANA JM ARRANZ I HARTO A LEDO A
Citation
Mi. Gomez et al., PLASMA-LEVELS OF 8-METHOXYPSORALEN AFTER BATH-PUVA FOR PSORIASIS - RELATIONSHIP TO DISEASE SEVERITY, British journal of dermatology, 133(1), 1995, pp. 37-40
Citations number
24
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
British journal of dermatology → ACNP
ISSN journal
00070963
Volume
133
Issue
1
Year of publication
1995
Pages
37 - 40
Database
ISI
SICI code
0007-0963(1995)133:1<37:PO8ABF>2.0.ZU;2-T
Abstract
Plasma levels of 8-methoxypsoralen (8-MOP) were determined by high-pre ssure liquid chromatography in 19 patients with psoriasis who were rec eiving bath-PUVA treatment, at different time points after the psorale n bath. The levels of 8-MOP varied between <5ng/ml (lower limit of det ection) and 34 ng/ml, and we found a relationship between the plasma p soralen levels and the severity of the disease.